› 1ohm

Solution NMR

Sakacin P variant that is structurally stabilized by an inserted C-terminal disulfide bridge.

Released:
DOI: 10.2210/pdb1ohm/pdb
PDB entry 1ohm coloured by chain, ensemble of 10 models, front view.
PDB entry 1ohm coloured by chain, ensemble of 10 models, side view.
PDB entry 1ohm coloured by chain, ensemble of 10 models, top view.
Source organism: Latilactobacillus sakei
Primary publication:
Three-dimensional structure in lipid micelles of the pediocin-like antimicrobial peptide sakacin P and a sakacin P variant that is structurally stabilized by an inserted C-terminal disulfide bridge.
Uteng M, Hauge HH, Markwick PR, Fimland G, Mantzilas D, Nissen-Meyer J, Muhle-Goll C
Biochemistry 42 11417-26 (2003)
PMID: 14516192

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152973 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bacteriocin sakacin-P Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 4.53 KDa
Source organism: Latilactobacillus sakei
Expression system: Latilactobacillus sakei
UniProt:
  • Canonical: P35618 (Residues: 19-61; Coverage: 71%)
Gene names: sakP, sakR, sppA
Sequence domains: Class II bacteriocin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: MOLECULAR DYNAMICS/ SIMULATED ANNEALING
Expression system: Latilactobacillus sakei

Quick links

Citations

10 review citations

Peptide antimicrobial agents.
Jenssen et al. (2006)
9 more

1 mention without citation

Pan-genomic and comparative analysis of Pediococcus pentosaceus focused on the in silico assessment of pediocin-like bacteriocins.
Rodrigues Blanco et al. (2022)