› 1oj1

X-ray diffraction
2.1Å resolution

Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA)

Released:
DOI: 10.2210/pdb1oj1/pdb
PDB entry 1oj1 coloured by chain, front view.
PDB entry 1oj1 coloured by chain, side view.
PDB entry 1oj1 coloured by chain, top view.
Source organism: Lithobates catesbeianus
Entry authors: Tsai C-J, Liu J-H, Liao Y-D, Chen L-y, Cheng P-T, Sun Y-J

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190112 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease A-domain domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 12.19 KDa
Source organism: Lithobates catesbeianus
UniProt:
  • Canonical: Q9DFY5 (Residues: 24-128; Coverage: 100%)
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:
Ligand CG2 1 x CG2
Ligand SO4 1 x SO4
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P43212
Unit cell:
a: 61.8Å b: 61.8Å c: 65.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.203 0.251

Quick links