› 1okf

Solution NMR

NMR structure of an alpha-L-LNA:RNA hybrid

Released:
DOI: 10.2210/pdb1okf/pdb
PDB entry 1okf coloured by chain, ensemble of 20 models, front view.
PDB entry 1okf coloured by chain, ensemble of 20 models, side view.
PDB entry 1okf coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
NMR structure of an alpha-L-LNA:RNA hybrid: structural implications for RNase H recognition.
Nielsen JT, Stein PC, Petersen M
Nucleic Acids Res 31 5858-67 (2003)
PMID: 14530434

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-114311 (preferred)
Entry contents:
1 distinct DNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
5'-D(*CP*ATLP*GP*AP*ATLP*AP*ATLP*GP*CP)-3' Chain: A
Molecule details ›
Chain: A
Length: 9 nucleotides
Theoretical weight: 2.81 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-R(*GP*CP*AP*UP*AP*UP*CP*AP*GP)-3' Chain: B
Molecule details ›
Chain: B
Length: 9 nucleotides
Theoretical weight: 2.86 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand ATL 3 x ATL

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology.
Østergaard et al. (2011)
1 more

1 mention without citation

NMR structure of an alpha-L-LNA:RNA hybrid: structural implications for RNase H recognition.
Nielsen et al. (2003)