› 1oks

X-ray diffraction
1.8Å resolution

Crystal structure of the measles virus phosphoprotein XD domain

Released:
DOI: 10.2210/pdb1oks/pdb
PDB entry 1oks coloured by chain, front view.
PDB entry 1oks coloured by chain, side view.
PDB entry 1oks coloured by chain, top view.
Source organism: Measles morbillivirus
Primary publication:
Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein.
Johansson K, Bourhis JM, Campanacci V, Cambillau C, Canard B, Longhi S
J Biol Chem 278 44567-73 (2003)
PMID: 12944395

Function and Biology Details

Reaction catalysed: 
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137000 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoprotein Chain: A
Molecule details ›
Chain: A
Length: 56 amino acids
Theoretical weight: 6.89 KDa
Source organism: Measles morbillivirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03422 (Residues: 459-507; Coverage: 10%)
Gene name: P/V
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

1 bound ligand:
Ligand NHE 1 x NHE
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P3221
Unit cell:
a: 50.109Å b: 50.109Å c: 47.127Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.239
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling.
Uversky et al. (2005)
17 more

16 mentions without citation

Macromolecular ab initio phasing enforcing secondary and tertiary structure.
Millán et al. (2015)
15 more