› 1oll

X-ray diffraction
1.93Å resolution

Extracellular region of the human receptor NKp46

Released:
DOI: 10.2210/pdb1oll/pdb
PDB entry 1oll coloured by chain, front view.
PDB entry 1oll coloured by chain, side view.
PDB entry 1oll coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the human NK cell triggering receptor NKp46 ectodomain.
Ponassi M, Cantoni C, Biassoni R, Conte R, Spallarossa A, Pesce A, Moretta A, Moretta L, Bolognesi M, Bordo D
Biochem Biophys Res Commun 309 317-23 (2003)
PMID: 12951052

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131189 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Natural cytotoxicity triggering receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 188 amino acids
Theoretical weight: 21.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O76036 (Residues: 25-212; Coverage: 66%)
Gene names: LY94, NCR1
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P61
Unit cell:
a: 85.477Å b: 85.477Å c: 59.909Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.195 0.251
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Natural cytotoxicity receptors and their ligands.
Kruse et al. (2014)
6 more

5 mentions without citation

The structural basis of ligand recognition by natural killer cell receptors.
Joyce et al. (2011)
4 more