› 1om9

X-ray diffraction
2.5Å resolution

Structure of the GGA1-appendage in complex with the p56 binding peptide

Released:
DOI: 10.2210/pdb1om9/pdb
PDB entry 1om9 coloured by chain, front view.
PDB entry 1om9 coloured by chain, side view.
PDB entry 1om9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for binding of accessory proteins by the appendage domain of GGAs.
Collins BM, Praefcke GJ, Robinson MS, Owen DJ
Nat Struct Biol 10 607-13 (2003)
PMID: 12858163

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-182288 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ADP-ribosylation factor-binding protein GGA1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 154 amino acids
Theoretical weight: 17.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJY5 (Residues: 494-639; Coverage: 23%)
Gene name: GGA1
Sequence domains: Adaptin C-terminal domain
Structure domains: Immunoglobulin-like
Coiled-coil domain-containing protein 91 Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 15 amino acids
Theoretical weight: 1.65 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q7Z6B0 (Residues: 2-16; Coverage: 3%)
Gene names: CCDC91, GGABP, HSD8

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3121
Unit cell:
a: 61.414Å b: 61.414Å c: 145.008Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.213 0.262
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

10 review citations

Adaptors for clathrin coats: structure and function.
Owen et al. (2004)
9 more

2 mentions without citation

Structure of Golgi transport proteins.
Kümmel et al. (2011)
1 more