› 1omk

X-ray diffraction
1.3Å resolution

The Crystal Structure of d(CACG(5IU)G)

Released:
DOI: 10.2210/pdb1omk/pdb
PDB entry 1omk coloured by chain, front view.
PDB entry 1omk coloured by chain, side view.
PDB entry 1omk coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Exploration of the influence of 5-iodo-2'-deoxyuridine incorporation on the structure of d[CACG(IDU)G].
Schuerman G, Van Hecke K, Van Meervelt L
Acta Crystallogr D Biol Crystallogr 59 1525-8 (2003)
PMID: 12876373

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114314 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*AP*CP*GP*(5IU)P*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.92 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NCO 2 x NCO
1 modified residue:
Ligand 5IU 2 x 5IU

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 18.155Å b: 30.034Å c: 41.988Å
α: 90° β: 90° γ: 90°
Expression system: Not provided

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Citations

1 citations in other articles

Induction of A:T to G:C transition mutations by 5-(2-chloroethyl)-2'-deoxyuridine (CEDU), an antiviral pyrimidine nucleoside analogue, in the bone marrow of Muta Mouse.
Staedtler et al. (2004)

3 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
2 more