› 1oqk

Solution NMR

Structure of Mth11: A homologue of human RNase P protein Rpp29

Released:
DOI: 10.2210/pdb1oqk/pdb
PDB entry 1oqk coloured by chain, ensemble of 22 models, front view.
PDB entry 1oqk coloured by chain, ensemble of 22 models, side view.
PDB entry 1oqk coloured by chain, ensemble of 22 models, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P.
Boomershine WP, McElroy CA, Tsai HY, Wilson RC, Gopalan V, Foster MP
Proc Natl Acad Sci U S A 100 15398-403 (2003)
PMID: 14673079

Function and Biology Details

Reaction catalysed: 
Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease P protein component 1 Chain: A
Molecule details ›
Chain: A
Length: 97 amino acids
Theoretical weight: 11.16 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O26119 (Residues: 2-93; Coverage: 99%)
Gene names: MTH_11, rnp1
Sequence domains: Ribonuclease P/MRP, subunit p29
Structure domains: Ribonuclease P/MRP, subunit p29

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

9 review citations

RNase P: interface of the RNA and protein worlds.
Evans et al. (2006)
8 more

2 mentions without citation

Of proteins and RNA: the RNase P/MRP family.
Esakova et al. (2010)
1 more