Function and Biology Details
Reaction catalysed:
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Thiamin diphosphate-binding fold
- Pyruvate decarboxylase/indolepyruvate decarboxylase-like
- TPP-binding enzyme, conserved site
- Thiamine pyrophosphate enzyme, TPP-binding
- Pyruvate decarboxylase/indolepyruvate decarboxylase-like, PP-binding domain
- Thiamine pyrophosphate enzyme, central domain
- DHS-like NAD/FAD-binding domain superfamily
- Pyruvate decarboxylase/indolepyruvate decarboxylase-like, pyrimidine-binding domain
2 more domains
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Indole-3-pyruvate decarboxylase (preferred)
PDBe Complex ID:
PDB-CPX-149899 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Indole-3-pyruvate decarboxylase
Molecule details ›
Chains: A, B, C, D
Length: 552 amino acids
Theoretical weight: 60.09 KDa
Source organism: Enterobacter cloacae
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 552 amino acids
Theoretical weight: 60.09 KDa
Source organism: Enterobacter cloacae
Expression system: Escherichia coli
UniProt:
- Canonical:
P23234 (Residues: 1-552; Coverage: 100%)
Sequence domains:
- Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
- Thiamine pyrophosphate enzyme, central domain
- Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
