› 1p2f

X-ray diffraction
1.8Å resolution

Crystal Structure Analysis of Response Regulator DrrB, a Thermotoga maritima OmpR/PhoB Homolog

Released:
DOI: 10.2210/pdb1p2f/pdb
PDB entry 1p2f coloured by chain, front view.
PDB entry 1p2f coloured by chain, side view.
PDB entry 1p2f coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Structural analysis of the domain interface in DrrB, a response regulator of the OmpR/PhoB subfamily.
Robinson VL, Wu T, Stock AM
J Bacteriol 185 4186-94 (2003)
PMID: 12837793

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194445 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Response regulator Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 25.79 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9WXY0 (Residues: 3-220; Coverage: 99%)
Gene name: TM_0126
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 57.89Å b: 59.39Å c: 77.64Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.224
Expression system: Escherichia coli BL21(DE3)

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Citations

7 review citations

Specificity in two-component signal transduction pathways.
Laub et al. (2007)
6 more

17 mentions without citation

Bacterial response regulators: versatile regulatory strategies from common domains.
Gao et al. (2007)
16 more