› 1p3x

Solution NMR

INTRAMOLECULAR DNA TRIPLEX WITH 1-PROPYNYL DEOXYURIDINE IN THE THIRD STRAND, NMR, 10 STRUCTURES

Released:
DOI: 10.2210/pdb1p3x/pdb
PDB entry 1p3x coloured by chain, ensemble of 10 models, front view.
PDB entry 1p3x coloured by chain, ensemble of 10 models, side view.
PDB entry 1p3x coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
Solution structure of an intramolecular DNA triplex containing 5-(1-propynyl)-2'-deoxyuridine residues in the third strand.
Phipps AK, Tarköy M, Schultze P, Feigon J
Biochemistry 37 5820-30 (1998)
PMID: 9558315

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-243659 (preferred)
Entry contents:
3 distinct DNA molecules
Macromolecules (3 distinct):
DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*A)-3') Chain: A
Molecule details ›
Chain: A
Length: 8 nucleotides
Theoretical weight: 2.51 KDa
Source organism: synthetic construct
Expression system: Not provided
DNA (5'-D(*TP*TP*CP*TP*CP*TP*CP*T)-3') Chain: B
Molecule details ›
Chain: B
Length: 8 nucleotides
Theoretical weight: 2.34 KDa
Source organism: synthetic construct
Expression system: Not provided
DNA (5'-D(*(PDU)P*CP*(PDU)P*(DCM)P*(PDU)P*CP*(PDU)P*(PDU))-3') Chain: C
Molecule details ›
Chain: C
Length: 8 nucleotides
Theoretical weight: 2.46 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY/ SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

3 review citations

Multistranded DNA structures.
Gilbert et al. (1999)
2 more

1 mention without citation

Three's a crowd - stabilisation, structure, and applications of DNA triplexes.
Dalla Pozza et al. (2022)