› 1p4p

X-ray diffraction
2Å resolution

Outer Surface Protein B of B. burgdorferi: crystal structure of the C-terminal fragment

Released:
DOI: 10.2210/pdb1p4p/pdb
PDB entry 1p4p coloured by chain, front view.
PDB entry 1p4p coloured by chain, side view.
PDB entry 1p4p coloured by chain, top view.
Source organism: Borreliella burgdorferi
Primary publication:
Structural investigation of Borrelia burgdorferi OspB, a bactericidal Fab target.
Becker M, Bunikis J, Lade BD, Dunn JJ, Barbour AG, Lawson CL
J Biol Chem 280 17363-70 (2005)
PMID: 15713683

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148153 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer surface protein B Chain: A
Molecule details ›
Chain: A
Length: 145 amino acids
Theoretical weight: 15.65 KDa
Source organism: Borreliella burgdorferi
Expression system: Escherichia coli
UniProt:
  • Canonical: P17739 (Residues: 152-296; Coverage: 52%)
Gene names: BB_A16, ospB
Sequence domains: Borrelia lipoprotein
Structure domains: Outer Surface Protein A; domain 3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: C2221
Unit cell:
a: 30.8Å b: 51.66Å c: 158.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.26
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The role of Borrelia burgdorferi outer surface proteins.
Kenedy et al. (2012)
1 more

2 mentions without citation

A generic approach to evaluate how B-cell epitopes are surface-exposed on protein structures.
Lollier et al. (2011)
1 more