› 1p68

Solution NMR

Solution structure of S-824, a de novo designed four helix bundle

Released:
DOI: 10.2210/pdb1p68/pdb
PDB entry 1p68 coloured by chain, ensemble of 15 models, front view.
PDB entry 1p68 coloured by chain, ensemble of 15 models, side view.
PDB entry 1p68 coloured by chain, ensemble of 15 models, top view.
Source organism: Escherichia coli
Primary publication:
Solution structure of a de novo protein from a designed combinatorial library.
Wei Y, Kim S, Fela D, Baum J, Hecht MH
Proc Natl Acad Sci U S A 100 13270-3 (2003)
PMID: 14593201

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
De novo designed protein S-824 Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.95 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
Structure domains: Designed four-helix bundle protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

Protein design by directed evolution.
Jäckel et al. (2008)
9 more

10 mentions without citation

Hierarchical design of artificial proteins and complexes toward synthetic structural biology.
Arai R. (2018)
9 more