› 1p79

X-ray diffraction
1.1Å resolution

Crystal structure of a bulged RNA tetraplex: implications for a novel binding site in RNA tetraplex

Released:
DOI: 10.2210/pdb1p79/pdb
PDB entry 1p79 coloured by chain, front view.
PDB entry 1p79 coloured by chain, side view.
PDB entry 1p79 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of a bulged RNA tetraplex at 1.1 a resolution: implications for a novel binding site in RNA tetraplex.
Pan B, Xiong Y, Shi K, Sundaralingam M
Structure 11 1423-30 (2003)
PMID: 14604532

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196160 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
5'-R(*UP*GP*UP*GP*GP*U)-3' Chain: A
Molecule details ›
Chain: A
Length: 6 nucleotides
Theoretical weight: 1.91 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand K 3 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: P4212
Unit cell:
a: 35.014Å b: 35.014Å c: 22.257Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.127 0.127 0.136
Expression system: Not provided

Quick links

Citations

4 review citations

The application of DNA and RNA G-quadruplexes to therapeutic medicines.
Collie et al. (2011)
3 more

4 mentions without citation

Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.
Meier et al. (2018)
3 more