Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
3C-like proteinase (preferred)
PDBe Complex ID:
PDB-CPX-143063 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3C-like proteinase
Molecule details ›
Chains: A, B
Length: 300 amino acids
Theoretical weight: 33.31 KDa
Source organism: Human coronavirus 229E
Expression system: Escherichia coli
UniProt:
Sequence domains: Coronavirus endopeptidase C30
Structure domains:
Length: 300 amino acids
Theoretical weight: 33.31 KDa
Source organism: Human coronavirus 229E
Expression system: Escherichia coli
UniProt:
- Canonical:
P0C6U2 (Residues: 2966-3265; Coverage: 7%)
Sequence domains: Coronavirus endopeptidase C30
Structure domains:
