Function and Biology Details
Reaction catalysed:
Hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Caricain (preferred)
PDBe Complex ID:
PDB-CPX-145152 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Caricain
Molecule details ›
Chains: A, B, C
Length: 322 amino acids
Theoretical weight: 35.94 KDa
Source organism: Carica papaya
Expression system: Escherichia coli
UniProt:
Structure domains: Cysteine proteinases
Length: 322 amino acids
Theoretical weight: 35.94 KDa
Source organism: Carica papaya
Expression system: Escherichia coli
UniProt:
- Canonical:
P10056 (Residues: 27-348; Coverage: 97%)
Structure domains: Cysteine proteinases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SRS BEAMLINE PX9.6
Spacegroup:
C2221
Expression system: Escherichia coli
