› 1pd1

X-ray diffraction
2.6Å resolution

Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide containing the DxE cargo sorting signal of yeast Sys1 protein

Released:
DOI: 10.2210/pdb1pd1/pdb
PDB entry 1pd1 coloured by chain, front view.
PDB entry 1pd1 coloured by chain, side view.
PDB entry 1pd1 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
SNARE selectivity of the COPII coat.
Mossessova E, Bickford LC, Goldberg J
Cell 114 483-95 (2003)
PMID: 12941276

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154122 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein transport protein SEC24 Chain: A
Molecule details ›
Chain: A
Length: 810 amino acids
Theoretical weight: 90.84 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P40482 (Residues: 117-926; Coverage: 88%)
Gene names: ANU1, SEC24, YIL109C
Sequence domains:
Structure domains:
DxE cargo sorting signal peptide of yeast Sys1 protein Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 1.07 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: P3221
Unit cell:
a: 93.949Å b: 93.949Å c: 199.927Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.203 0.256
Expression system: Not provided

Quick links

Citations

71 review citations

SNAREs--engines for membrane fusion.
Jahn et al. (2006)
70 more