› 1pfp

X-ray diffraction
2.3Å resolution

CATHELIN-LIKE MOTIF OF PROTEGRIN-3

Released:
DOI: 10.2210/pdb1pfp/pdb
PDB entry 1pfp coloured by chain, front view.
PDB entry 1pfp coloured by chain, side view.
PDB entry 1pfp coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Selenomethionine and selenocysteine double labeling strategy for crystallographic phasing.
Strub MP, Hoh F, Sanchez JF, Strub JM, Böck A, Aumelas A, Dumas C
Structure 11 1359-67 (2003)
PMID: 14604526

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152229 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protegrin-3 Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 11.97 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P32196 (Residues: 30-130; Coverage: 84%)
Gene name: NPG3
Sequence domains: Cathelicidin
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 1 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P6522
Unit cell:
a: 51.541Å b: 51.541Å c: 134.512Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.219 0.284
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Discovery, synthesis, and structure-activity relationships of conotoxins.
Akondi et al. (2014)
6 more

2 mentions without citation

Systematic comparison of crystal and NMR protein structures deposited in the protein data bank.
Sikic et al. (2010)
1 more