› 1pk3

X-ray diffraction
1.85Å resolution

Scm SAM domain

Released:
DOI: 10.2210/pdb1pk3/pdb
PDB entry 1pk3 coloured by chain, front view.
PDB entry 1pk3 coloured by chain, side view.
PDB entry 1pk3 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
Kim CA, Sawaya MR, Cascio D, Kim W, Bowie JU
J Biol Chem 280 27769-75 (2005)
PMID: 15905166

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194251 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polycomb protein Scm Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 89 amino acids
Theoretical weight: 10.38 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9VHA0 (Residues: 795-871; Coverage: 9%)
Gene names: CG9495, Scm
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

1 bound ligand:
Ligand BME 3 x BME
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-D
Spacegroup: P212121
Unit cell:
a: 52.15Å b: 63.993Å c: 103.638Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.231
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Polycomb group protein-mediated repression of transcription.
Morey et al. (2010)
14 more

3 mentions without citation

Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila.
McElroy et al. (2014)
2 more