› 1plf

X-ray diffraction
2.2Å resolution

THE THREE-DIMENSIONAL STRUCTURE OF BOVINE PLATELET FACTOR 4 AT 3.0 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1plf/pdb
PDB entry 1plf coloured by chain, front view.
PDB entry 1plf coloured by chain, side view.
PDB entry 1plf coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The three-dimensional structure of bovine platelet factor 4 at 3.0-A resolution.
St Charles R, Walz DA, Edwards BF
J Biol Chem 264 2092-9 (1989)
PMID: 2914894

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136203 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Platelet factor 4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 72 amino acids
Theoretical weight: 7.89 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P02777 (Residues: 14-83; Coverage: 80%)
Gene names: CXCL4, PF4, SCYB4
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:
Ligand TCN 1 x TCN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 63.7Å b: 68Å c: 80.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 not available
Expression system: Not provided

Quick links

Citations

14 review citations

Human chemokines: an update.
Baggiolini et al. (1997)
13 more

2 mentions without citation

Nanoscale dewetting transition in protein complex folding.
Hua et al. (2007)
1 more