› 1q2k

Solution NMR

Solution structure of BmBKTx1 a new potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch

Released:
DOI: 10.2210/pdb1q2k/pdb
PDB entry 1q2k coloured by chain, ensemble of 21 models, front view.
PDB entry 1q2k coloured by chain, ensemble of 21 models, side view.
PDB entry 1q2k coloured by chain, ensemble of 21 models, top view.
Source organism: Mesobuthus martensii
Primary publication:
Solution structure of BmBKTx1, a new BKCa1 channel blocker from the Chinese scorpion Buthus martensi Karsch.
Cai Z, Xu C, Xu Y, Lu W, Chi CW, Shi Y, Wu J
Biochemistry 43 3764-71 (2004)
PMID: 15049683

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 19.1 Chain: A
Molecule details ›
Chain: A
Length: 31 amino acids
Theoretical weight: 3.35 KDa
Source organism: Mesobuthus martensii
Expression system: Not provided
UniProt:
  • Canonical: P83407 (Residues: 1-31; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, energy minimization
Expression system: Not provided

Quick links

Citations

12 citation in other articles

Turning a scorpion toxin into an antitumor miniprotein.
Li et al. (2008)
11 more

3 mentions without citation

Peptide toxins and small-molecule blockers of BK channels.
Yu et al. (2016)
2 more