› 1q3t

Solution NMR

Solution structure and function of an essential CMP kinase of Streptococcus pneumoniae

Released:
DOI: 10.2210/pdb1q3t/pdb
PDB entry 1q3t coloured by chain, front view.
PDB entry 1q3t coloured by chain, side view.
PDB entry 1q3t coloured by chain, top view.
Source organism: Streptococcus pneumoniae
Primary publication:
Solution structure and function of an essential CMP kinase of Streptococcus pneumoniae.
Yu L, Mack J, Hajduk PJ, Kakavas SJ, Saiki AY, Lerner CG, Olejniczak ET
Protein Sci 12 2613-21 (2003)
PMID: 14573872

Function and Biology Details

Reaction catalysed: 
ATP + (d)CMP = ADP + (d)CDP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytidylate kinase Chain: A
Molecule details ›
Chain: A
Length: 236 amino acids
Theoretical weight: 26.31 KDa
Source organism: Streptococcus pneumoniae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q97PK6 (Residues: 1-223; Coverage: 100%)
Gene names: SP_1603, cmk
Sequence domains: Cytidylate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Prophylaxis and therapy of plague.
Oyston et al. (2013)
10 other articles

5 mentions without citation

The Blueprint of a Minimal Cell: MiniBacillus.
Reuß et al. (2016)
4 more