› 1q50

X-ray diffraction
2.6Å resolution

Phosphoglucose isomerase from Leishmania mexicana.

Released:
DOI: 10.2210/pdb1q50/pdb
PDB entry 1q50 coloured by chain, front view.
PDB entry 1q50 coloured by chain, side view.
PDB entry 1q50 coloured by chain, top view.
Source organism: Leishmania mexicana
Primary publication:
The crystal structure of glucose-6-phosphate isomerase from Leishmania mexicana reveals novel active site features.
Cordeiro AT, Michels PA, Delboni LF, Thiemann OH
Eur J Biochem 271 2765-72 (2004)
PMID: 15206941

Function and Biology Details

Reaction catalysed: 
Alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154901 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chain: A
Molecule details ›
Chain: A
Length: 561 amino acids
Theoretical weight: 62.45 KDa
Source organism: Leishmania mexicana
Expression system: Escherichia coli
UniProt:
  • Canonical: P42861 (Residues: 44-604; Coverage: 93%)
Gene name: PGI
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P6122
Unit cell:
a: 85.744Å b: 85.744Å c: 350.429Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.195 0.25
Expression system: Escherichia coli

Quick links

Citations

15 citation in other articles

Excretory-secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrata.
Guillou et al. (2007)
14 more

7 mentions without citation

Copaifera of the Neotropics: A Review of the Phytochemistry and Pharmacology.
da Trindade et al. (2018)
6 more