› 1q8h

X-ray diffraction
2Å resolution

Crystal structure of porcine osteocalcin

Released:
DOI: 10.2210/pdb1q8h/pdb
PDB entry 1q8h coloured by chain, front view.
PDB entry 1q8h coloured by chain, side view.
PDB entry 1q8h coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Bone recognition mechanism of porcine osteocalcin from crystal structure.
Hoang QQ, Sicheri F, Howard AJ, Yang DS
Nature 425 977-80 (2003)
PMID: 14586470

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184618 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Osteocalcin Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.73 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q8HYY9 (Residues: 1-49; Coverage: 100%)
Gene name: BGLAP

Ligands and Environments

1 bound ligand:
Ligand CA 3 x CA
1 modified residue:
Ligand CGU 3 x CGU

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P3121
Unit cell:
a: 51.491Å b: 51.491Å c: 35.389Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.272 0.255 0.283

Quick links

Citations

54 review citations

Biomimetic model systems for investigating the amorphous precursor pathway and its role in biomineralization.
Gower LB. (2008)
53 more

9 mentions without citation

Using the RosettaSurface algorithm to predict protein structure at mineral surfaces.
Pacella et al. (2013)
8 more