› 1qbz

X-ray diffraction
1.47Å resolution

THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A

Released:
DOI: 10.2210/pdb1qbz/pdb
PDB entry 1qbz coloured by chain, front view.
PDB entry 1qbz coloured by chain, side view.
PDB entry 1qbz coloured by chain, top view.
Source organism: Simian immunodeficiency virus
Primary publication:
The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution.
Yang ZN, Mueser TC, Kaufman J, Stahl SJ, Wingfield PT, Hyde CC
J Struct Biol 126 131-44 (1999)
PMID: 10388624

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-123055 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein gp160 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 123 amino acids
Theoretical weight: 14.43 KDa
Source organism: Simian immunodeficiency virus
Expression system: Escherichia coli
UniProt:
  • Canonical: E7CWP5 (Residues: 552-674; Coverage: 14%)
Gene name: env
Sequence domains: Retroviral envelope protein
Structure domains: Helix Hairpins

Ligands and Environments

3 bound ligands:
Ligand HG 2 x HG
Ligand MRD 2 x MRD
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: C2
Unit cell:
a: 91.124Å b: 47.206Å c: 77.465Å
α: 90° β: 100.83° γ: 90°
R-values:
R R work R free
0.155 not available 0.218
Expression system: Escherichia coli

Quick links

Citations

7 review citations

The structural biology of type I viral membrane fusion.
Colman et al. (2003)
6 more

8 mentions without citation

HIV-1 diversity in the envelope glycoproteins: implications for viral entry inhibition.
Araújo et al. (2013)
7 more