› 1qd8

X-ray diffraction
1Å resolution

COMPLEX OF VANCOMYCIN WITH N-ACETYL GLYCINE

Released:
DOI: 10.2210/pdb1qd8/pdb
PDB entry 1qd8 coloured by chain, front view.
PDB entry 1qd8 coloured by chain, side view.
PDB entry 1qd8 coloured by chain, top view.
Source organism: Amycolatopsis orientalis
Primary publication:
Vancomycin binding to low-affinity ligands: delineating a minimum set of interactions necessary for high-affinity binding.
Loll PJ, Kaplan J, Selinsky BS, Axelsen PH
J Med Chem 42 4714-9 (1999)
PMID: 10579833

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162408 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
VANCOMYCIN Chains: A, B
Molecule details ›
Chains: A, B
Length: 7 amino acids
Theoretical weight: 1.15 KDa
Source organism: Amycolatopsis orientalis
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, RER
Carbohydrate polymer
2 bound ligands:
Ligand CL 3 x CL
Ligand AAC 1 x AAC
2 modified residues:
Ligand GHP 4 x GHP
Ligand OMY 2 x OMY

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P43212
Unit cell:
a: 28.71Å b: 28.71Å c: 66.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.11 not available 0.131
Expression system: Not provided

Quick links

Citations

2 review citations

Mechanism of action of oritavancin and related glycopeptide antibiotics.
Allen et al. (2003)
1 more

2 mentions without citation

Nature's nitrite-to-ammonia expressway, with no stop at dinitrogen.
Kroneck PMH. (2022)
1 more