› 1qdd

X-ray diffraction
1.3Å resolution

CRYSTAL STRUCTURE OF HUMAN LITHOSTATHINE TO 1.3 A RESOLUTION

Released:
DOI: 10.2210/pdb1qdd/pdb
PDB entry 1qdd coloured by chain, front view.
PDB entry 1qdd coloured by chain, side view.
PDB entry 1qdd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mechanism of calcite crystal growth inhibition by the N-terminal undecapeptide of lithostathine.
Gerbaud V, Pignol D, Loret E, Bertrand JA, Berland Y, Fontecilla-Camps JC, Canselier JP, Gabas N, Verdier JM
J Biol Chem 275 1057-64 (2000)
PMID: 10625646

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138672 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lithostathine-1-alpha Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05451 (Residues: 23-166; Coverage: 100%)
Gene names: PSPS, PSPS1, REG, REG1A
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

Carbohydrate polymer : NEW Components: NDG, GAL, SIA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: P65
Unit cell:
a: 48Å b: 48Å c: 111Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.132 not available 0.159

Quick links

Citations

5 review citations

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
4 more

16 mentions without citation

Marine Antifreeze Proteins: Structure, Function, and Application to Cryopreservation as a Potential Cryoprotectant.
Kim et al. (2017)
15 more