› 1qdp

Solution NMR

SOLUTION STRUCTURE OF ROBUSTOXIN, THE LETHAL NEUROTOXIN FROM THE FUNNEL WEB SPIDER ATRAX ROBUSTUS, NMR, 20 STRUCTURES

Released:
DOI: 10.2210/pdb1qdp/pdb
PDB entry 1qdp coloured by chain, ensemble of 20 models, front view.
PDB entry 1qdp coloured by chain, ensemble of 20 models, side view.
PDB entry 1qdp coloured by chain, ensemble of 20 models, top view.
Source organism: Atrax robustus
Primary publication:
Solution structure of robustoxin, the lethal neurotoxin from the funnel-web spider Atrax robustus.
Pallaghy PK, Alewood D, Alewood PF, Norton RS
FEBS Lett 419 191-6 (1997)
PMID: 9428632

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134324 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Delta-hexatoxin-Ar1a Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.86 KDa
Source organism: Atrax robustus
UniProt:
  • Canonical: P01478 (Residues: 1-42; Coverage: 100%)
Sequence domains: Delta Atracotoxin
Structure domains: Omega-AgatoxinV

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED SIMULATED ANNEALING

Quick links

Citations

10 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
9 more

6 mentions without citation

Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Buczek et al. (2007)
5 more