› 1qk6

Solution NMR

Solution structure of huwentoxin-I by NMR

Released:
DOI: 10.2210/pdb1qk6/pdb
PDB entry 1qk6 coloured by chain, ensemble of 10 models, front view.
PDB entry 1qk6 coloured by chain, ensemble of 10 models, side view.
PDB entry 1qk6 coloured by chain, ensemble of 10 models, top view.
Source organism: Cyriopagopus schmidti
Primary publication:
Proton nuclear magnetic resonance studies on huwentoxin-I from the venom of the spider Selenocosmia huwena: 2. Three-dimensional structure in solution.
Qu Y, Liang S, Ding J, Liu X, Zhang R, Gu X
J Protein Chem 16 565-74 (1997)
PMID: 9263120

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157516 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mu/omega-theraphotoxin-Hs1a Chain: A
Molecule details ›
Chain: A
Length: 33 amino acids
Theoretical weight: 3.76 KDa
Source organism: Cyriopagopus schmidti
UniProt:
  • Canonical: P56676 (Residues: 49-81; Coverage: 55%)
Sequence domains: Ion channel inhibitory toxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry

Quick links

Citations

8 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
7 more

4 mentions without citation

Functional expression of spider neurotoxic peptide huwentoxin-I in E. coli.
Meng et al. (2011)
3 more