› 1qkg

Solution NMR

DNA DECAMER DUPLEX CONTAINING T-T DEWAR PHOTOPRODUCT

Released:
DOI: 10.2210/pdb1qkg/pdb
PDB entry 1qkg coloured by chain, front view.
PDB entry 1qkg coloured by chain, side view.
PDB entry 1qkg coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The Dewar photoproduct of thymidylyl(3'-->5')- thymidine (Dewar product) exhibits mutagenic behavior in accordance with the "A rule".
Lee JH, Bae SH, Choi BS
Proc Natl Acad Sci U S A 97 4591-6 (2000)
PMID: 10758155

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114437 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*GP*CP*AP*(HYD)TP*+TP*AP*CP*GP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.01 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*GP*CP*GP*TP*GP*AP*TP*GP*CP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.1 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
2 modified residues:
Ligand 64T 1 x 64T
Ligand TA3 1 x TA3

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 38%
Refinement method: SIMULATED ANNEALING AND FULL RELAXATION MATRIX REFINEMENT
Expression system: Not provided

Quick links

Citations

6 review citations

Direct and indirect effects of UV radiation on DNA and its components.
Ravanat et al. (2001)
5 more

4 mentions without citation

Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.
Rastogi et al. (2010)
3 more