› 1qlc

Solution NMR

Solution structure of the second PDZ domain of Postsynaptic Density-95

Released:
DOI: 10.2210/pdb1qlc/pdb
PDB entry 1qlc coloured by chain, ensemble of 20 models, front view.
PDB entry 1qlc coloured by chain, ensemble of 20 models, side view.
PDB entry 1qlc coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95.
Tochio H, Hung F, Li M, Bredt DS, Zhang M
J Mol Biol 295 225-37 (2000)
PMID: 10623522

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151877 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 4 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 9.98 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P31016 (Residues: 155-249; Coverage: 13%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

6 review citations

PDZ domains and the organization of supramolecular complexes.
Sheng et al. (2001)
5 more

4 mentions without citation

SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis.
Galande et al. (2001)
3 more