› 1qnj

X-ray diffraction
1.1Å resolution

THE STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT ATOMIC RESOLUTION (1.1 A)

Released:
DOI: 10.2210/pdb1qnj/pdb
PDB entry 1qnj coloured by chain, front view.
PDB entry 1qnj coloured by chain, side view.
PDB entry 1qnj coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Atomic resolution structure of native porcine pancreatic elastase at 1.1 A.
Würtele M, Hahn M, Hilpert K, Höhne W
Acta Crystallogr D Biol Crystallogr 56 520-3 (2000)
PMID: 10739939

Function and Biology Details

Reaction catalysed: 
Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133451 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chymotrypsin-like elastase family member 1 Chain: A
Molecule details ›
Chain: A
Length: 240 amino acids
Theoretical weight: 25.93 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00772 (Residues: 27-266; Coverage: 96%)
Gene names: CELA1, ELA1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 49.91Å b: 57.82Å c: 74.27Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.127 not available 0.165

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Citations

1 review citation

Sub-Angstrom resolution enzyme X-ray structures: is seeing believing?
Vrielink et al. (2003)
11 other articles

16 mentions without citation

Structural composition of betaI- and betaII-proteins.
Sreerama et al. (2003)
15 more