› 1qqu

X-ray diffraction
1.63Å resolution

CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH BOUND ACETATE ION

Released:
DOI: 10.2210/pdb1qqu/pdb
PDB entry 1qqu coloured by chain, front view.
PDB entry 1qqu coloured by chain, side view.
PDB entry 1qqu coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Crystal structure at 1.63 A resolution of the native form of porcine beta-trypsin: revealing an acetate ion binding site and functional water network.
Johnson A, Gautham N, Pattabhi V
Biochim Biophys Acta 1435 7-21 (1999)
PMID: 10561533

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trypsin Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.49 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00761 (Residues: 9-231; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 78Å b: 53.9Å c: 47.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.255

Quick links

Citations

6 citation in other articles

Structural basis for intramembrane proteolysis by rhomboid serine proteases.
Ben-Shem et al. (2007)
5 more

5 mentions without citation

The ClusPro web server for protein-protein docking.
Kozakov et al. (2017)
4 more