› 1qsk

Solution NMR

NMR-DERIVED SOLUTION STRUCTURE OF A FIVE-ADENINE BULGE LOOP WITHIN A DNA DUPLEX

Released:
DOI: 10.2210/pdb1qsk/pdb
PDB entry 1qsk coloured by chain, ensemble of 15 models, front view.
PDB entry 1qsk coloured by chain, ensemble of 15 models, side view.
PDB entry 1qsk coloured by chain, ensemble of 15 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a five-adenine bulge loop within a DNA duplex.
Dornberger U, Hillisch A, Gollmick FA, Fritzsche H, Diekmann S
Biochemistry 38 12860-8 (1999)
PMID: 10504256

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114467 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(GP*CP*AP*TP*CP*GP*AP*AP*AP*AP*AP*GP*CP*TP*AP*CP*GP)-3' Chain: A
Molecule details ›
Chain: A
Length: 17 nucleotides
Theoretical weight: 5.23 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*CP)-3' Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS AND RESTRAINED ENERGY MINIMIZATION
Expression system: Not provided

Quick links

Citations

2 review citations

Recent advances in FRET: distance determination in protein-DNA complexes.
Hillisch et al. (2001)
1 more

4 mentions without citation

Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation.
Dowen et al. (2010)
3 more