› 1qu1

X-ray diffraction
1.9Å resolution

CRYSTAL STRUCTURE OF EHA2 (23-185)

Released:
DOI: 10.2210/pdb1qu1/pdb
PDB entry 1qu1 coloured by chain, front view.
PDB entry 1qu1 coloured by chain, side view.
PDB entry 1qu1 coloured by chain, top view.
Source organism: Influenza A virus
Primary publication:
N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.
Chen J, Skehel JJ, Wiley DC
Proc Natl Acad Sci U S A 96 8967-72 (1999)
PMID: 10430879

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137029 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin HA2 chain Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 155 amino acids
Theoretical weight: 18.06 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03437 (Residues: 376-530; Coverage: 28%)
Gene name: HA
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: C2
Unit cell:
a: 113.241Å b: 48.877Å c: 221.303Å
α: 90° β: 103.26° γ: 90°
R-values:
R R work R free
0.229 0.229 0.25
Expression system: Escherichia coli

Quick links

Citations

36 review citations

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.
Skehel et al. (2000)
35 more

44 mentions without citation

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
43 more