Function and Biology Details
Reaction catalysed:
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ribosomal RNA adenine methyltransferase KsgA/Erm
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- Ribosomal RNA adenine dimethylase
- rRNA adenine dimethylase-like, C-terminal
- Ribosomal RNA adenine methylase transferase, conserved site
- Ribosomal RNA adenine methylase transferase, N-terminal
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Ribosomal RNA small subunit methyltransferase A (preferred)
PDBe Complex ID:
PDB-CPX-139325 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosomal RNA small subunit methyltransferase A
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 27.99 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Ribosomal RNA adenine dimethylase
Structure domains:
Length: 252 amino acids
Theoretical weight: 27.99 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P06992 (Residues: 17-268; Coverage: 92%)
Sequence domains: Ribosomal RNA adenine dimethylase
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU
Spacegroup:
C2
Expression system: Escherichia coli
