› 1qzx

X-ray diffraction
4Å resolution

Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication

Released:
DOI: 10.2210/pdb1qzx/pdb
PDB entry 1qzx coloured by chain, front view.
PDB entry 1qzx coloured by chain, side view.
PDB entry 1qzx coloured by chain, top view.
Source organism: Saccharolobus solfataricus
Primary publication:
Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication.
Rosendal KR, Wild K, Montoya G, Sinning I
Proc Natl Acad Sci U S A 100 14701-6 (2003)
PMID: 14657338

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189073 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal recognition particle 54 kDa protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 440 amino acids
Theoretical weight: 49.46 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q97ZE7 (Residues: 1-432; Coverage: 97%)
Gene names: SSO0971, srp54
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: I4
Unit cell:
a: 197.906Å b: 197.906Å c: 64.305Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.313 0.313 0.383
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Signal recognition particle: an essential protein-targeting machine.
Akopian et al. (2013)
18 more

4 mentions without citation

Archaea signal recognition particle shows the way.
Zwieb et al. (2010)
3 more