› 1r29

X-ray diffraction
1.3Å resolution

Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB Domain to 1.3 Angstrom

Released:
DOI: 10.2210/pdb1r29/pdb
PDB entry 1r29 coloured by chain, front view.
PDB entry 1r29 coloured by chain, side view.
PDB entry 1r29 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Ahmad KF, Melnick A, Lax S, Bouchard D, Liu J, Kiang CL, Mayer S, Takahashi S, Licht JD, Privé GG
Mol Cell 12 1551-64 (2003)
PMID: 14690607

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154263 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B-cell lymphoma 6 protein Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P41182 (Residues: 5-129; Coverage: 18%)
Gene names: BCL5, BCL6, LAZ3, ZBTB27, ZNF51
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: C2
Unit cell:
a: 30.606Å b: 71.849Å c: 55.414Å
α: 90° β: 105.91° γ: 90°
R-values:
R R work R free
0.131 0.128 0.173
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

45 review citations

The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway.
Baird et al. (2020)
44 more

13 mentions without citation

Sequence and structural analysis of BTB domain proteins.
Stogios et al. (2005)
12 more