› 1r4d

Solution NMR

Solution structure of the chimeric L/D DNA oligonucleotide d(C8metGCGC(L)G(L)CGCG)2

Released:
DOI: 10.2210/pdb1r4d/pdb
PDB entry 1r4d coloured by chain, ensemble of 11 models, front view.
PDB entry 1r4d coloured by chain, ensemble of 11 models, side view.
PDB entry 1r4d coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
L-nucleotides and 8-methylguanine of d(C1m8G2C3G4C5LG6LC7G8C9G10)2 act cooperatively to promote a left-handed helix under physiological salt conditions.
Cherrak I, Mauffret O, Santamaria F, Hocquet A, Ghomi M, Rayner B, Fermandjian S
Nucleic Acids Res 31 6986-95 (2003)
PMID: 14627831

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114495 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*(8MG)P*CP*GP*(0DC)P*(0DG)P*CP*GP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.06 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
3 modified residues:
Ligand 8MG 2 x 8MG
Ligand 0DC 2 x 0DC
Ligand 0DG 2 x 0DG

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics followed by cartesian dynamics
Expression system: Not provided

Quick links

Citations

1 review citation

Exploring the role of chirality in nucleic acid recognition.
D'Alonzo et al. (2011)
1 other article

1 mention without citation

Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering.
An et al. (2009)