› 1r5a

X-ray diffraction
2.5Å resolution

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190414 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
glutathione transferase Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 25.06 KDa
Source organism: Anopheles cracens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GQG7 (Residues: 1-218; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GTS 1 x GTS
1 bound ligand:
Ligand CU 3 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: I4122
Unit cell:
a: 122.129Å b: 122.129Å c: 74.699Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.265
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Computational methods in drug discovery.
Sliwoski et al. (2014)
6 more

9 mentions without citation

Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme.
Udomsinprasert et al. (2005)
8 more