1r5t

X-ray diffraction
2Å resolution

The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast

Released:

Function and Biology Details

Reaction catalysed:
2'-deoxycytidine + H(2)O = 2'-deoxyuridine + NH(3)
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170365 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytidine deaminase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 142 amino acids
Theoretical weight: 15.55 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06549 (Residues: 1-142; Coverage: 100%)
Gene names: CDD1, L9672.13, YLR245C
Sequence domains: Cytidine and deoxycytidylate deaminase zinc-binding region
Structure domains: Cytidine Deaminase, domain 2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: C2221
Unit cell:
a: 78.52Å b: 86.37Å c: 156.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.188 0.222
Expression system: Escherichia coli