› 1r6b

X-ray diffraction
2.25Å resolution

High resolution crystal structure of ClpA

Released:
DOI: 10.2210/pdb1r6b/pdb
PDB entry 1r6b coloured by chain, front view.
PDB entry 1r6b coloured by chain, side view.
PDB entry 1r6b coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
Xia D, Esser L, Singh SK, Guo F, Maurizi MR
J Struct Biol 146 166-79
PMID: 15037248

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142166 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent Clp protease ATP-binding subunit ClpA Chain: X
Molecule details ›
Chain: X
Length: 758 amino acids
Theoretical weight: 84.3 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABH9 (Residues: 1-758; Coverage: 100%)
Gene names: JW0866, b0882, clpA, lopD
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MG 3 x MG
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P65
Unit cell:
a: 124.11Å b: 124.11Å c: 97.049Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.234 0.278
Expression system: Escherichia coli

Quick links

Citations

7 review citations

AAA+ proteins: have engine, will work.
Hanson et al. (2005)
6 more

14 mentions without citation

A newly discovered protein export machine in malaria parasites.
de Koning-Ward et al. (2009)
13 more