› 1rcs

Solution NMR

NMR STUDY OF TRP REPRESSOR-OPERATOR DNA COMPLEX

Released:
DOI: 10.2210/pdb1rcs/pdb
PDB entry 1rcs coloured by chain, ensemble of 15 models, front view.
PDB entry 1rcs coloured by chain, ensemble of 15 models, side view.
PDB entry 1rcs coloured by chain, ensemble of 15 models, top view.
Source organism: Escherichia coli
Primary publication:
The solution structures of the trp repressor-operator DNA complex.
Zhang H, Zhao D, Revington M, Lee W, Jia X, Arrowsmith C, Jardetzky O
J Mol Biol 238 592-614 (1994)
PMID: 8176748

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114512 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Trp operon repressor Chains: A, B
Molecule details ›
Chains: A, B
Length: 105 amino acids
Theoretical weight: 12.04 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P0A881 (Residues: 4-108; Coverage: 97%)
Gene names: JW4356, b4393, rtrY, trpR
Sequence domains: Trp repressor protein
Structure domains: TrpR-like
DNA (5'-D(*CP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*TP*AP*CP*G)-3') Chains: E, F
Molecule details ›
Chains: E, F
Length: 20 nucleotides
Theoretical weight: 6.13 KDa
Source organism: Escherichia coli
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand TRP 2 x TRP
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

11 review citations

The use of 2H, 13C, 15N multidimensional NMR to study the structure and dynamics of proteins.
Gardner et al. (1998)
10 more

1 mention without citation

Structural analysis of conserved base pairs in protein-DNA complexes.
Mirny et al. (2002)