› 1ro3

Solution NMR

New structural insights on short disintegrin echistatin by NMR

Released:
DOI: 10.2210/pdb1ro3/pdb
PDB entry 1ro3 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ro3 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ro3 coloured by chain, ensemble of 20 models, top view.
Source organism: Echis carinatus
Primary publication:
Conformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMR.
Monleón D, Esteve V, Kovacs H, Calvete JJ, Celda B
Biochem J 387 57-66 (2005)
PMID: 15535803

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148041 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disintegrin echistatin Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.44 KDa
Source organism: Echis carinatus
UniProt:
  • Canonical: P17347 (Residues: 131-179; Coverage: 26%)
Sequence domains: Disintegrin
Structure domains: Disintegrin domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: Initial manual assignment of unambiguous NOEs and extension and confirmation of NOE assignments by 20 cycle sof NOAH standard routines

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Citations

2 review citations

Snake venom metalloproteases--structure and function of catalytic and disintegrin domains.
Ramos et al. (2006)
1 more

3 mentions without citation

Snake Venom Metalloproteinases (SVMPs): A structure-function update.
Olaoba et al. (2020)
2 more