› 1rqy

X-ray diffraction
1.55Å resolution

9-amino-[N-(2-dimethylamino)proply]-acridine-4-carboxamide bound to d(CGTACG)2

Released:
DOI: 10.2210/pdb1rqy/pdb
PDB entry 1rqy coloured by chain, front view.
PDB entry 1rqy coloured by chain, side view.
PDB entry 1rqy coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of 9-amino-[N-(2-dimethylamino)propyl]acridine-4-carboxamide bound to d(CGTACG)(2): a comparison of structures of d(CGTACG)(2) complexed with intercalatorsin the presence of cobalt.
Adams A, Guss JM, Denny WA, Wakelin LP
Acta Crystallogr D Biol Crystallogr 60 823-8 (2004)
PMID: 15103127

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114531 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(CP*GP*TP*AP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand CO 2 x CO
Ligand 7AD 3 x 7AD
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C222
Unit cell:
a: 28.745Å b: 52.124Å c: 40.745Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.226 0.286
Expression system: Not provided

Quick links

Citations

1 review citation

Non-G Base Tetrads.
Escaja et al. (2022)
5 other articles

4 mentions without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)
3 more