› 1rtc

X-ray diffraction
2.3Å resolution

THE STRUCTURE OF RECOMBINANT RICIN A CHAIN AT 2.3 ANGSTROMS

Released:
DOI: 10.2210/pdb1rtc/pdb
Model geometry
Fit model/data
Data not deposited
PDB entry 1rtc coloured by chain, front view.
PDB entry 1rtc coloured by chain, side view.
PDB entry 1rtc coloured by chain, top view.
Source organism: Ricinus communis
Primary publication:
Structure of recombinant ricin A chain at 2.3 A.
Mlsna D, Monzingo AF, Katzin BJ, Ernst S, Robertus JD
Protein Sci 2 429-35 (1993)
PMID: 8453380

Function and Biology Details

Reaction catalysed: 
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136287 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ricin A chain Chain: A
Molecule details ›
Chain: A
Length: 268 amino acids
Theoretical weight: 30.07 KDa
Source organism: Ricinus communis
Expression system: Not provided
UniProt:
  • Canonical: P02879 (Residues: 36-302; Coverage: 49%)
Sequence domains: Ribosome inactivating protein
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
Spacegroup: P21
Unit cell:
a: 42.6Å b: 68.1Å c: 50.2Å
α: 90° β: 112.9° γ: 90°
R-values:
R R work R free
0.23 0.23 not available
Expression system: Not provided

Quick links

Citations

9 review citations

Ricin. Mechanisms of cytotoxicity.
Lord et al. (2003)
8 more

36 mentions without citation

Passive and active vaccination strategies to prevent ricin poisoning.
Pincus et al. (2011)
35 more