› 1rv9

X-ray diffraction
1.53Å resolution

Crystal Structure of Neisseria meningitidis protein NMB0706, Pfam DUF152

Released:
DOI: 10.2210/pdb1rv9/pdb
PDB entry 1rv9 coloured by chain, front view.
PDB entry 1rv9 coloured by chain, side view.
PDB entry 1rv9 coloured by chain, top view.
Source organism: Neisseria meningitidis
Entry authors: Eswaramoorthy S, Swaminathan S, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reactions catalysed: 
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate
S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate
2'-deoxyadenosine + H(2)O = 2'-deoxyinosine + NH(3)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191719 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Purine nucleoside phosphorylase Chain: A
Molecule details ›
Chain: A
Length: 259 amino acids
Theoretical weight: 27.15 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9K0A8 (Residues: 1-259; Coverage: 100%)
Gene name: NMB0706
Sequence domains: Multi-copper polyphenol oxidoreductase laccase
Structure domains: CNF1/YfiH-like putative cysteine hydrolases

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: C2
Unit cell:
a: 78.85Å b: 41.34Å c: 72.14Å
α: 90° β: 99.34° γ: 90°
R-values:
R R work R free
0.197 0.197 0.21
Expression system: Escherichia coli

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