› 1s0t

Solution NMR

Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV

Released:
DOI: 10.2210/pdb1s0t/pdb
PDB entry 1s0t coloured by chain, front view.
PDB entry 1s0t coloured by chain, side view.
PDB entry 1s0t coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV.
Aramini JM, Cleaver SH, Pon RT, Cunningham RP, Germann MW
J Mol Biol 338 77-91 (2004)
PMID: 15050824

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114561 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*Gp*Tp*Cp*Cp*(A3A)p*Cp*Gp*Ap*Cp*G)-3' Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.03 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*Cp*Gp*Tp*Cp*Gp*Tp*Gp*Gp*Ap*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.06 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand A3A 1 x A3A

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics molecular dynamics
Expression system: Not provided

Quick links

Citations

3 review citations

Recognition of damaged DNA: structure and dynamic markers.
Germann et al. (2012)
2 more

1 mention without citation

Epimeric 2-deoxyribose lesions: Products from the improper chemical repair of 2-deoxyribose radicals.
Amato et al. (2014)