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› 1s58

X-ray diffraction
3.5Å resolution

The structure of B19 parvovirus capsid

Released:
DOI: 10.2210/pdb1s58/pdb
Model geometry
Fit model/data
PDB entry 1s58 coloured by chain, front view.
PDB entry 1s58 coloured by chain, side view.
PDB entry 1s58 coloured by chain, top view.
Source organism: Human parvovirus B19
Primary publication:
The structure of human parvovirus B19.
Kaufmann B, Simpson AA, Rossmann MG
Proc Natl Acad Sci U S A 101 11628-33 (2004)
PMID: 15289612

Function and Biology Details

Reaction catalysed: 
a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192956 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Minor capsid protein VP1 Chain: A
Molecule details ›
Chain: A
Length: 554 amino acids
Theoretical weight: 60.93 KDa
Source organism: Human parvovirus B19
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9PZT0 (Residues: 228-781; Coverage: 71%)
Gene name: vp
Sequence domains: Parvovirus coat protein VP2
Structure domains: Parvovirus coat protein VP1/VP2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: P213
Unit cell:
a: 351.393Å b: 351.393Å c: 351.393Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.313 0.313 0.316
Expression system: Spodoptera frugiperda

Quick links

Citations

16 review citations

Human Parvoviruses.
Qiu et al. (2017)
15 more

20 mentions without citation

Therapeutic Potential of Engineered Virus-like Particles of Parvovirus B19.
Sánchez-Moguel et al. (2023)
19 more