› 1s6x

Solution NMR

Solution structure of VSTx

Released:
DOI: 10.2210/pdb1s6x/pdb
PDB entry 1s6x coloured by chain, ensemble of 20 models, front view.
PDB entry 1s6x coloured by chain, ensemble of 20 models, side view.
PDB entry 1s6x coloured by chain, ensemble of 20 models, top view.
Source organism: Grammostola rosea
Primary publication:
Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel.
Jung HJ, Lee JY, Kim SH, Eu YJ, Shin SY, Milescu M, Swartz KJ, Kim JI
Biochemistry 44 6015-23 (2005)
PMID: 15835890

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158159 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kappa-theraphotoxin-Gr3a Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 4.01 KDa
Source organism: Grammostola rosea
Expression system: Not provided
UniProt:
  • Canonical: P60980 (Residues: 30-63; Coverage: 81%)
Sequence domains: Ion channel inhibitory toxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Not provided

Quick links

Citations

14 review citations

Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.
Rodríguez de la Vega et al. (2005)
13 more

8 mentions without citation

Tarantula toxins interacting with voltage sensors in potassium channels.
Swartz KJ. (2007)
7 more